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Sophos System Protection Service startup type got set "Manual" and cannot change it back to Automatic

Sophos System Protection Service startup type got set "Manual" and get Access is denied when I try to change it to Automatic

My domain login is member of the Administrators group on the local machine. However, impossible for me to stop and/or change the startup type of this service: getting "Access is denied." when clicking Apply.

Also, impossible for me to access the folder "C:\ProgramData\Sophos\Endpoint Defense", it says 

Any ideas about what could be wrong?



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