Exchange 2013

i installed server endpoint protection on our exchange server 2013 and in the end I had to remove it because it crippled it practically crippled the server, I read that sophos had a template to exclude files automatically but I feel that there was more going on, and in the end I had to use the sophos zap tool to remove the application....

is there any more guidance on exclusion and recommendations to put in place before i attempt to put the sophos endpoint protection back on