Recipient address rejected: Access denied error on Email Gateway


I am currently in trial mode and doing some email sending with a test domain. It is a hosted on MS 365

I believe I have everything setup correctly but I am receiving this error when sending from an outside address

Any ideas on what may be wrong 

Reporting-MTA: dns;
Arrival-Date: Thu, 11 Aug 2022 16:25:56 -0700 (PDT)
X-Original-Message-ID: <>

Final-Recipient: rfc822;
Action: failed
Status: 5.7.1
Remote-MTA: dns; (, the server for
the domain
Diagnostic-Code: smtp; 554 5.7.1 <>: Recipient address rejected: Access denied
Last-Attempt-Date: Thu, 11 Aug 2022 16:25:58 -0700 (PDT)



Parents Reply
  • I spoke to our account manager who confirmed that the early adopters of Sophos Central ( August 2021 ) has to specifically ask to have their instance is a certain region.

    It is only later on the one got the option of selecting a region on first setup.

    Apparently it is possible to migrate and we are working towards that now.

    Will keep you posted on how it goes

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