We have Exchange 2013 install in a DAG scenario.
2 Exchange 2013 Server configured with DAG.
Is installing PureMessage on both 2 Exchange 2013 Servers as a separate instance a viable approach ?
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We have Exchange 2013 install in a DAG scenario.
2 Exchange 2013 Server configured with DAG.
Is installing PureMessage on both 2 Exchange 2013 Servers as a separate instance a viable approach ?
Unfortunately no. I ran into this issue myself. Per Appendix A: You must have either a local clustered SQL Server instance, or a remote SQL Server instance.
What I did is point the PureMessage to my server running Sophos Enterprise Console. PureMessage then sets up a quarantine on the remote server for both Exchange Servers. So far it has been working fine! 
Cal Ebey