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Endpoint causing Solarwinds website to stop functioning while endpoint in lockdown

Hello Group, 

We recently rebuilt our Solarwinds application servers, and our Orion server which hosts the Solarwinds website using Microsoft IIS as the platform, keeps shutting down after enabling lockdown in Sophos Endpoint.  The other non-website servers have no services that stop, but the orion server has the website shut down randomly.  Removing the lockdown seems to resolve the issue. 

Any thoughts on non-standard exceptions for Sophos that would prevent this from happening? 

Thanks in advance for suggestions,