Please be aware that Sophos recently expand the function with Sophos Central for macOS version 10.0.1. You should re-visit your JAMF profile and add the Live Response and MDR component. For more details - please check the following KBA:support.sophos.com/.../KB-000039014
In addition - please see the current community entry about:
community.sophos.com/.../sophos-mac-endpoint-how-to-configure-jamf-privacy-preferences-for-10-15-compatibility