Since Upgrade to MR4 I can reproduce this error when doing any GUI Packet capture and clicking 28 (or some times a few more) times in a row on the refresh button.
only thing that helps then is logging in with SSH and executing:
service tomcat:restart -ds nosync

Any browser.

Userportal on other port still works when WebAdmin is generating the error 500.

Never noticed the issue in MR1 and used the packet capture option regularly there.
See logs:
tomcat.log
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2021-01-11 12:58:05,954:INFO:CSC - EventBean: { opCode: manage_page_detail, mode: 301, waitForeResponse: true, reques tType: 1, opcodetype: 0, entityId: 39, beanName: null, syncalbe: true, comProtocol: u }
2021-01-11 12:58:06,483:ERROR: - EXCEPTION IN RESULTSET WRAPPER WHILE EXECUTING QUERY: java.lang.NullPointerException java.lang.NullPointerException
at com.elitecore.jdbchelper.ResultSetWrapper.<init>(ResultSetWrapper.java:40)
at com.elitecore.jdbchelper.SqlReader.getResultSetWrapper(SqlReader.java:199)
at com.sophos.sf.auth.AuthHelper.isRefererCheckRequired(AuthHelper.java:105)
at com.sophos.sf.auth.AuthHelper.hasValidReferer(AuthHelper.java:128)
at com.sophos.sf.auth.HttpSessionHelper.isExpired(HttpSessionHelper.java:59)
at com.sophos.sf.auth.HttpSessionHelper.isExpired(HttpSessionHelper.java:29)
at cyberoam.sessionmanagement.SessionCheckFilter.doFilter(SessionCheckFilter.java:69)
at org.eclipse.jetty.servlet.ServletHandler$CachedChain.doFilter(ServletHandler.java:1602)
at org.eclipse.jetty.servlet.ServletHandler.doHandle(ServletHandler.java:540)
at org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:146)
at org.eclipse.jetty.security.SecurityHandler.handle(SecurityHandler.java:548)
at org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:132)
at org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:257)
at org.eclipse.jetty.server.session.SessionHandler.doHandle(SessionHandler.java:1701)
at org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:255)
at org.eclipse.jetty.server.handler.ContextHandler.doHandle(ContextHandler.java:1345)
at org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:203)
at org.eclipse.jetty.servlet.ServletHandler.doScope(ServletHandler.java:480)
at org.eclipse.jetty.server.session.SessionHandler.doScope(SessionHandler.java:1668)
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