I am having the same activation issues as everyone else (Windows completely up to date, all the suggested checkboxes checked, etc.). If it helps at all, my Office applications would not run either (I was not trying to run them inside Sandboxie). After uninstalling Sandboxie 5.30 my Office applications would run again. When will this issue be fixed? I have the "lifetime license" on multiple computers at home and this is a real pain in the you-know-what.