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"Sophos Anti-Virus for Windows 2000+: removing W32/Confick and Mal/Conficker

After downloading the "Sophos Anti-Virus for Windows 2000+:removing W32/Confick and Mal/Conficker with Sophos Anti-Virus" this is the message that I'm getting.....any ideas of what is wrong....

Log file path: C:\WINDOWS\TEMP\Sophos_MalConficker-A.log

Could not open C:\Documents and Settings\LocalService\Local Settings\Application Data\Microsoft\Windows\UsrClass.dat
Could not open C:\Documents and Settings\LocalService\Local Settings\Application Data\Microsoft\Windows\UsrClass.dat.LOG
Could not open C:\Documents and Settings\NetworkService\Local Settings\Application Data\Microsoft\Windows\UsrClass.dat

We are having this Conficker-A and Conficker-D really bad at school...and it's getting on flash drives that I bring back and forth....Webroot is not cleaning ....

HELP

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