Error on Sophos Email appliances - host 127.0.0.1[127.0.0.1] said: 450 try later (in reply to end of DATA command)

Question

Hi Guys, 
 
 Our Sophos Email Appliances are showing an error and not delivering mail, which is stuck in the "Pre-Filter deferred" queue. 
 We are also seeing this error: 
 host 127.0.0.1[127.0.0.1] said: 450 try later (in reply to end of DATA command) 
 
 Is anyone else getting this? Sophos Support say they are having a massive worldwide problem with Sophos Email Appliances today, but I'm not seeing anyone talking about the problem which I was expecting. 
 
 Thanks 
 
 Radek

Sure Win · Accepted Answer

Please follow the knowledge base article for the latest information Sophos Email Appliance: milter hangs causing mail flow to stop

Radek Tkaczyk · Answer

Hi Guys, 
 
 Finally got onto someone at Sophos Support: 02 9409 9100 
 
 Looks like a bad definition update. You have to get Sophos on the phone, get them to do a remote session to your SEA and they rebuild the antivirus definition file on your SEA. 
 
 Still struggling to get ours done here. 
 
 Radek

Aditya Patel · Answer

Hi All, 
 As this issue affected many customers , I would strongly recommend to contact Support to get this issue resolved .

Abhijit Deshpande · Answer

Hello, 
 
 Just got a callback from Sophos Support and got fix as well on one of the appliance. 
 
 Thanks Team for immediate help here. 
 
 Regards, 
 Abhijit Deshpande