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Unable to permanently remove Mal/DrodCab_A

Sophos is detecting the file Mal/DrodCab_A on my iMac OS X Yosemite v. 10.10.3 but I am unable to permanently delete it. Can't get a file path and often the file disappears before or as soon as I unlock the computer to deal with the threat file. Sophos seems to detect the threat only when I am connected to the Internet, but I'm not 100% sure about this. Anyone have experience with this threat? Is it a serious threat? If so, what do I do to deal with it?

Sophos Anti-Virus.log shows the following:

com.sophos.intercheck: 2015-04-22 15:47:14 +1000 Threat: 'Mal/DrodCab-A' detected in 

com.sophos.intercheck:                                               Access to the file denied

Thanks in advance for any help.

:1020685


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