BigSur with Sophos Endpoint - OneDrive for Business files don't download

Hi, When trying to download a file in OneDrive whether using Files on-demand in the OneDrive client or not they don't.
The issue occurs whether it is the onedrive of the user or a SharePoint library.

With files on-demand enabled, all the placeholder files and folders come down fine but if you double click to open the OneDrive download box comes up but progress bar and downloaded size doesn't go up. After about a minute it times out with error code 16.

With files on-demand turned off no files download and OneDrive sits ttrying to sync processing changes but don't download.

No detections or events are shown in the client or Sophos Central.

I have gone through Admin Login in the Sophos client and disabled all options but it is still the same.

If i uninstall Sophos Endpoint then OneDrive works as normal.

Any help to get to the bottom of this would be massively appreciated.

Thanks
Mike