Can I Run Sophos in a Win10 Hyper V VM

Jordan,

Yes you can.

Now, this does not protect the host server, the server OS, nor the hypervisor.  This means that there is always a way that malware can still get in even if you have Sophos Home installed in the VM.

To protect the server, its OS and the virtualization environment as well as all the data traveling in and out of it, you can purchase Sophos Server Protection.  If you are using VMWare, you can also use VMWare NSX.   Other options also exist from a variety of vendors.

Hi 
In fact you can protect the Hyperviseur (the Host OS) 

you just need to create 2 vswitch : 

An external for the Firewall 

and an internal one for the lan network with an adapter for the sophos firewall and an other for the host 

So in this setup you can protect the server with the sophos Firewall

And for host setup you can also test Virtualization Security with Hyper-V or WMWare  www.sophos.com/.../virtualization-security.aspx

And for host setup you can also test Virtualization Security with Hyper-V or WMWare  www.sophos.com/.../virtualization-security.aspx