I received this mail from Appleseed this morning 12/Feb/2016
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Engineering has implemented changes that are supposed to fix the problem you reported. These changes are in the latest version of the software available to you, 15E39d (OS X 10.11.4 Seed 3).
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I have applied the update with the SIP enabled and restarted. Good news the SOPHOS AV is now running. I have applied this updated to a Mac Mini and to a 2009 MacPro running SOPHOS AV Home Edition 9.4.2
Peter Sleet
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