You need to have the option that most other phishing simulators have which is "Whitelist by Email Headers" Most other vendors have some kind of customer headers so that they can be whitelisted by rule in Office 365 mail. Without this feature Office 365 will mark all your simulation emilas as spam.
How knowbe4 does it: https://knowbe4.zendesk.com/hc/en-us/articles/212723707
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