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Issues with server protection on file server

Has anyone seen any issues with Sophos Central on file servers? 

We moved from on the on premises version of Sophos to the Sophos Cloud version.  When I updated our main file servers we started running into an issue where a server would stop serving files after a while (a few hours on the most active one/two weeks on another).  When on the desktop of the server everything seems fine. No CPU/memory/disk issue, \\server\share works fine locally.  

Remotely \\server\share just hangs for 30+ seconds until the connection times out.   Nothing seems to get the server running again except rebooting the whole thing.  It will then work fine for a while then break.   I can't find anything the event log or Sophos logging to point me in the direction of what is breaking.  

After I uninstalled Sophos on the busiest server the issue hasn't returned.  

 

Has anyone run into anything similar? 

 

I do have a ticket created with support.  At this point they just want me to test disabling features one by one until I can narrow the problem down.  I am trying to recreate the issue without needing actual users traffic.  I personally suspect the Cryptoguard (Intercept X?) since that is the part that is also causing us grief on the client side.



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