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Interferences between antivirus systems

Hello ! - I am using Mac with OS 10.9.5 and I have a question: Can there be interferences between antivirus systems ? - I have ClamXav (v2.14/0.99.2 (3295)) and Sophos Anti-Virus (Home Edition v 9.6.1). Sophos has found some malware now and then, while ClamXav never found any and claims that there can be interferences (as they experience e.g. with Avast which routinely removes ClamXAV's virus definitions database !) and that one should have only one Anti-Virus system. - What are the experiences here?



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