Sophos Central Endpoint and SEC: Computers fail/hang on boot after the Microsoft Windows April 9, 2019 update. Please follow knowledge base article 133945
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I just found out using the OpenVAS scanner that STAS is affected by the Microsoft Windows Unquoted Path Vulnerability Windows. Uninstall registry entries and services using an unquoted path containing at least one whitespace allow a local attacker with low privileges and write permissions to place a malicious executable.
Sophos Transparent Authentication Suite|STAS|C:\Program Files (x86)\Sophos\Sophos Transparent Authentication Suite\stas.exe
Hopefully this is fixed soon.
Would suggest to open a Support Case.