Sophos Central Endpoint and SEC: Computers fail/hang on boot after the Microsoft Windows April 9, 2019 update. Please follow knowledge base article 133945
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I'm a long time user of LastPass and have always found it secure and trustworthy. I noticed yesterday that Sophos had scanned it (possibly an update, I'm not sure) and tagged it as a Low Reputation App.
I'm hoping this is just a glitch, but would appreciate your confirmation.
The app reputation depends on multiple factors, If you trust the app then I suggest you submit the app for reassessment. Please refer to the article How to request an app reassessment to increase your app reputation. Let me know if this helps resolve your query.